Proteomics and metabolic engineering of prokaryotes (PMEP)
Metabolism biochemistry of microorganisms of applicative interest
Fermentation, enzymology, proteomics and metabolite analysis are the main approaches that we are currently using for in depth-understanding of the metabolism of microorganisms of applicative interest:
Development of consolidated bioprocessings for waste biomass conversion into high-value products
Economic viability of biorefinery strategies, producing high added-value molecules by microbial fermentation, relies on the utilization of cheap substrates and processes. Waste lignocellulosic biomass is among the most attractive raw materials because of its high abundance, low price and reneawability. However, current waste biomass bioconversions are economically inefficient multistep processes. Our research projects aim to develop consolidated processings for one-step fermentation conversion of waste biomass (agro-industrial waste, municipal solid waste, industrial waste) into biofuels and bioplastics. Experimental strategies that are employed include both metabolic engineering of microbial strain by genetic techniques (rational engineering and in vivo evolution) and fermentation process optimization.